Contagion

Effects

• In each room, the first enemy killed will release a gas explosion and poison nearby enemies.
  • Poisoned enemies will also release gas upon death, spreading the effect.
    • Poisoned enemies do not need to die while the poison is still active to spread the effect.
  • The effect will also activate if a shopkeeper is destroyed before killing any enemies.
    • Re-entering a room and destroying another shopkeeper inside it will trigger the effect for a second time.

Notes

• The initial gas explosion deals 5 damage, and the poison deals Isaac's tear damage per tick, for 6 ticks.
• The gas explosion and poison can damage friendly enemies.

Synergies

• (Added in Repentance)(Gigante Bean) Gigante Bean: Greatly increases the size of the gas explosions, making the poison spread much more effectively.

Interactions

• Dr. Fetus: Bomb damage does not apply to poison damage.
• Epic Fetus: Missile damage does not apply to poison damage.
• Ipecac: Ipecac only applies a 2x multiplier as opposed to +40 to poison damage.
• Poison tears: No effect. Gas explosions will only be triggered by poison caused by Contagion
• (Second Hand) Second Hand: Poison duration is not affected.