Lusty Blood

Effects

• Each time an enemy is killed, Isaac gains a damage boost for the current room.
  • Each kill increases damage by 0.5, up to a maximum of 5 damage after 10 kills.

Synergies

• (Added in Repentance) Meat Cleaver: Both of the smaller enemies produced by Meat Cleaver add to the damage bonus, allowing rooms with few enemies to grant much more damage.
• (Samson's Lock) Samson's Lock: Both the item and the trinket stack, granting 1 damage per kill. With 100% proc rate on the Lock, Isaac may gain up to 10 damage after 10 kills.

Interactions

• (Added in Repentance) Uranus: Only enemies killed by icicles from statues, bombs, familiars and other sources will increment Lusty Blood counter, thus rendering Lusty Blood quite difficult to use.

Notes

• Some summoned enemies like Rag Man's Raglings do not trigger the effect when killed.
• Mr. Maw does not trigger the effects of Lusty Blood, even after splitting.
• Blowing up a shopkeeper will grant Isaac a damage bonus as well.