The Mulligan

Effects

Tears have a 1/6 chance of spawning allied Blue Flies when they hit an enemy.
This item belongs to the Beelzebub set. Collecting three items from this set will transform Isaac into a giant humanoid fly.

(Removed in Repentance) Because the Guppy transformation includes the guaranteed ability to spawn flies on hit, the Mulligan's effect is nullified. This means individual tears cannot spawn more than one fly per hit.
- (Added in Repentance) Guppy has been lowered to have a 50% chance of spawning a fly, allowing the 2 items to work together.
(Removed in Repentance) This item does not work for (Lilith) Lilith since the (Added in Afterbirth) Incubus tears do not count for her tears.
Items and trinkets that increase tear firing rate synergize well with the Mulligan.
This item is not affected by luck.

Brimstone: Constantly spawns blue flies when attacking.
Chocolate Milk: The Mulligan's ability isn't affected by the charge time, meaning rapidly firing uncharged shots will generate a ton of blue flies.
Cricket's Body / The Parasite: Has a 1/6 chance to spawn a fly on every hit by a split shot, which boosts the spawning of flies immensely.
(Added in Afterbirth †) Finger!: Rapidly spawns blue flies when pointed at an enemy.