Adrenaline

Effects

Gives Isaac a flat damage up based on how many empty Heart containers he has.
- (Removed in Repentance) The damage up given is 0.2 for each empty Red Heart container Isaac has.
  - (Added in Repentance) The damage up given is ((2 * MissingHearts) ^ 1.6) * 0.1, where MissingHearts is the number of full red hearts of health missing.
- Damage ups are only applied for every fully empty heart container.
This item belongs to the Spun set. Collecting three items from this set will transform Isaac into a buff berserker.

This item has no effect on characters that can't have any Red Heart containers, unless (Bone Heart) Bone Hearts are collected. If a Bone Heart is gone, so does the Adrenaline damage. This means that Adrenaline is only truly useless on (The Lost) The Lost.
This item affects both (Keeper) Keeper and (Tainted Keeper) Tainted Keeper; empty Coin Hearts increase damage.
As (The Forgotten) The Forgotten, empty Bone Hearts increase damage, but if the Bone Hearts are broken, the damage buff is taken away.

(Added in Repentance) Blood Oath: Activates the damage up effect of Adrenaline for the resulting empty heart containers at the start of each floor.