Spoon Bender 
Effects
- Grants homing tears.
Synergies
- (Added in Repentance)
Aquarius: Trail of creep is purple and homes in on enemies.
- (Azazel) Azazel /
Brimstone / (Added in Repentance) (Tainted Azazel) Tainted Azazel /
Technology /
Technology 2 / (Added in Afterbirth)
Tech X: Beams curve toward enemies.
- (Added in Afterbirth †)
Compound Fracture /
Cricket's Body /
The Parasite: Tears and split tears are homing.
Dr. Fetus: The bombs slide towards enemies.
- (Added in Afterbirth)
Marked: Tears will travel in the direction of the cross-hairs until close enough to home in on an enemy.
Mom's Knife: The knife curves towards enemies.
Interactions
- (Added in Afterbirth)
Epic Fetus: Cursor slides towards enemies.
- (Added in Repentance)
Eye of the Occult: Tears home in on enemies when not being maneuvered.
The Ludovico Technique: The tear will attempt to home towards a single target, even if it hits a different enemy on its way there, making it difficult to control.
- (Added in Repentance) The changes to homing tears make it nearly impossible to maintain control of the shot while it's near an enemy.
- (Added in Afterbirth †)
Technology Zero: The electricity is unaffected.