Worm Friend 
Effects
- Gives Isaac a Nerve Ending familiar that burrows out of the ground to grab enemies for 4 seconds. Grabbed enemies take damage over time, are slowed, and are unable to move.
- Worm Friend deals 4 damage per tick (8 per second), for a total of 32 damage per grab.
- Worm Friend can target and restrain bosses in addition to normal enemies, even including endgame bosses such as Ultra Greed.
Notes
- Enemies can avoid/escape being grabbed if they move fast enough, jump, or teleport.
- Worm friend must wait 5 seconds after losing/killing/releasing its target before it can attack another enemy.
- When playing as (Tainted Lazarus) Tainted Lazarus / (Dead Tainted Lazarus) Dead Tainted Lazarus, entering a room with Worm Friend active and then using
Flip to swap to the other character will keep Worm Friend active for the remainder of the room.