PHD 
Effects
- Identifies all pills upon pickup.
- Spawns a pill.
- Replenishes 2 red hearts.
- Adds 0-2 coins to the payout every time you use a Blood Donation Machine or
IV Bag.
- In hard mode, adds exactly 1 coin to the payout.
- Converts some "bad" pills into their "good" counterparts or removes their bad effects:
| Pill | Changes Into | | --- | --- | | Stat down pill | Stat up pill | | Amnesia | I can see forever! | | (Added in Afterbirth †) ??? | Telepills | | (Added in Afterbirth †) Addicted | Percs! | | (Added in Afterbirth †) I'm Excited!!! | I'm Drowsy... | | (Added in Afterbirth †) Paralysis | Pheromones | | (Added in Afterbirth †) Retro Vision | I can see forever! | | (Added in Afterbirth †) R U A Wizard? | Power Pill! | | (Added in Afterbirth †) X-Lax | Something's wrong... | | (Removed in Repentance) Bad Trip | Full Health | | (Added in Repentance) Bad Trip | Balls of Steel | | (Added in Repentance) Horf! | Gulp! | | (Added in Repentance) Experimental Pill | Only grants a stat up | | (Added in Repentance) Gold Pill | Only has positive effects | | Unchanged | | 48 Hour Energy | | Bad Gas | | Bombs are Key | | Explosive Diarrhea | | Hematemesis | | I can see forever! | | I Found Pills | | Lemon Party | | Pheromones | | Pretty Fly | | Puberty | | Telepills | | (Added in Afterbirth) Friends Till the End! | | (Added in Afterbirth) Infested! | | (Added in Afterbirth) Infested? | | (Added in Afterbirth) One makes you larger | | (Added in Afterbirth) One makes you small | | (Added in Afterbirth) Percs! | | (Added in Afterbirth) Power Pill! | | (Added in Afterbirth) Re-Lax | | (Added in Afterbirth / Removed in Afterbirth †) ??? | | (Added in Afterbirth / Removed in Afterbirth †) Addicted! | | (Added in Afterbirth / Removed in Afterbirth †) Retro Vision | | (Added in Afterbirth †) Feels Like I'm Walking on Sunshine! | | (Added in Afterbirth †) Gulp! | | (Added in Afterbirth †) Something's Wrong... | | (Added in Afterbirth †) Vurp! | | (Added in Afterbirth † / Removed in Repentance) Horf! | | (Removed in Afterbirth †) Paralysis | | (Removed in Afterbirth †) R U A Wizard? |
Notes
- Bad pills already obtained/dropped will be converted to their "good" counterparts.
- If PHD is lost in any way, such as rerolling by the
D4 or a Dice Room, or dropping it as (Added in Repentance) (Tainted Isaac) Tainted Isaac, pills will remain fully identified, but negative pills will not be converted. - (Added in Afterbirth †) Performing a RERUN with a character that held PHD will still prevent negative pills from spawning, but will no longer identify pills until used.
- As bad pills will turn into good pills, it is possible for two different colored pills to have the same effect.
Interactions
- (Added in Repentance)
False PHD: Pills can both be good or bad again. Taking a bad pill still applies the benefits from False PHD.