Quints

Effects

Upon killing enemies, spawns a stationary familiar in their place for the room, up to a maximum of 5. These familiars do not follow Isaac.
The following familiars can spawn:
This item belongs to the Conjoined set. Collecting three items from this set will transform Isaac into a three-faced version of himself.

Killing the heads thrown by Rag Man before they turn into a Ragling is not counted as a kill and will not spawn a baby.
Getting hit by an enemy and Spawning a Baby from the same enemy at the same time crashes the game.
The same familiar can spawn multiple times.
Despite being stationary, tear-shooting babies will still inherit Isaac's movement, angling their tears accordingly.
Enemies killed by Dark Esau count as yours and will spawn a baby.
During The Beast fight, familiars spawned by Quints stay on screen throughout the chase sequence.
When playing as (Tainted Lazarus) Tainted Lazarus, Quints will not disappear on Flip but instead give you the ability to spawn more Quints if you Flip again. This is very effective in Greed mode and Boss rush because you flip automatically when completing a wave, giving you more Quints for every other wave.

(Baby-Bender) Baby-Bender: All shooting familiars spawned are affected, save for Little Steven and Seraphim.
BFFS!: Affects Quints familiars, doubling their damage.
Box of Friends: Existing Quints familiars will not be duplicated, nor more will be created. If Isaac has no other familiars, the generated Demon Baby will hover with the Quints instead of following Isaac.
King Baby: Familiars do not follow King Baby, nor are the familiars aiming independently at enemies.
Sacrificial Altar: The item will be lost, and each spawned familiar counts as one sacrifice. If Quints is sacrificed first (or is the only item available to sacrifice) and at least two familiars are summoned, two Devil Room items will be spawned while only losing one item.