Scapular

Effects

Once per room, when Isaac is reduced to his last half heart (either red, soul, or black), the aura around his head temporarily vanishes and he is granted one Soul Heart.
- After re-entering a room, the ability can be triggered again.
- With Bone Hearts, the effect triggers on both half-filled and empty ones.

If the Scapular is active and Isaac is already at his last half heart, the effect won't trigger even on fatal damage.
(Added in Afterbirth) Scapular does not charge between waves in Greed mode, though it can still be recharged by moving between rooms.
Does not work with (The Lost) The Lost or (Keeper) Keeper, as they cannot reach the required heart value.
Reaching only half a heart remaining may be more difficult in Chapter 4 onwards, since all half-heart hits are upgraded to a full heart.
(Added in Repentance) Damage sources that count as "health donation" no longer activate Scapular. This includes Blood Donation Machines, Devil Beggars, Hell Games, Confessionals, IV Bag, Razor Blade, Blood Rights, (Added in Afterbirth †) Dull Razor, Sharp Plug, (Added in Afterbirth †) Shard of Glass, (Added in Repentance) Blood Bombs, and (Added in Repentance) Blood Oath. Sacrifice Rooms spikes still activate Scapular.

(Cursed Skull) Cursed Skull: Provided Scapular can always trigger, grants effective immortality, as the soul heart is always given before the teleport takes place.
- + The Wafer: Grants true immortality, plus one hit on the soul heart, allowing the player to get hit once before teleporting.